Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878672 | 0.80 | KIT (0.40) | KITOPRM1OPRD1OGFRL1PIK3CD | |
| SCHEMBL20011912 | 0.78 | POLB (0.47) | KITACHEPOLBGBA1CKS1B | |
| SCHEMBL30060994 | 0.78 | POLB (0.47) | KITACHEPOLBGBA1CKS1B | |
| SCHEMBL3876920 | 0.76 | KIT (0.45) | KITACHEPOLBGBA1CKS1B | |
| SCHEMBL28363803 | 0.76 | JAK1 (0.48) | KITPOLBGBA1CKS1BSKP1 | |
| SCHEMBL5068826 | 0.76 | GBA1 (0.46) | KITPOLBGBA1CKS1BSKP1 | |
| SCHEMBL22720253 | 0.74 | KCNH2 (0.42) | KITPOLBGBA1CKS1BSKP1 | |
| SCHEMBL30061006 | 0.74 | TLR9 (0.44) | KITPOLBGBA1CKS1BSKP1 | |
| SCHEMBL19995252 | 0.74 | TLR9 (0.44) | KITPOLBGBA1CKS1BSKP1 | |
| SCHEMBL13876130 | 0.74 | KIT (0.35) | KITOPRM1OPRD1OGFRL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |