Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878672 | 0.82 | KIT (0.40) | KITCNR1CNR2PIK3CDMAPT | |
| SCHEMBL13875676 | 0.78 | TRAP1 (0.37) | KDM4ENPSR1POLB | |
| SCHEMBL3879335 | 0.77 | NR1H2 (0.34) | CNR1CNR2ACHEDPP4GBA1 | |
| SCHEMBL1695032 | 0.76 | OPRM1 (0.42) | KITCNR1CNR2PIK3CDOPRM1 | |
| SCHEMBL13876131 | 0.74 | KIT (0.43) | KITCNR1CNR2ACHEPIK3CD | |
| SCHEMBL5719178 | 0.72 | DCTPP1 (0.43) | ACHEKDM4EMAPTTHRBOPRM1 | |
| SCHEMBL5719594 | 0.72 | GAA (0.41) | DPP4KCNH2SMN1; SMN2 | |
| SCHEMBL3873555 | 0.70 | KIT (0.37) | KITCNR1CNR2ACHEGBA1 | |
| SCHEMBL20011912 | 0.70 | POLB (0.47) | KITCNR1CNR2ACHEMAPT | |
| SCHEMBL30060994 | 0.70 | POLB (0.47) | KITCNR1CNR2ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |