Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.52 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 4/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875758 | 0.82 | SLC2A1 (0.55) | SLC2A1SLC2A3MAPTALDH1A1LMNA | |
| SCHEMBL3874202 | 0.79 | KIT (0.52) | SLC2A1SLC2A3CNR1CNR2KIT | |
| SCHEMBL30947672 | 0.79 | GPR119 (0.64) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2120938 | 0.79 | GPR119 (0.64) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3874827 | 0.77 | GPR119 (0.41) | SLC2A1SLC2A3CNR1CNR2KIT | |
| SCHEMBL6356496 | 0.75 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3883186 | 0.72 | KIT (0.45) | SLC2A1SLC2A3CNR1CNR2KIT | |
| SCHEMBL20423342 | 0.70 | GPR119 (0.50) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30672845 | 0.70 | GPR119 (0.50) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1584044 | 0.70 | GPR119 (0.48) | GPR119MAPTALDH1A1LMNAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |