Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29491152 | 0.86 | MAPT (0.44) | GPR119PIK3CAMAPTALDH1A1LMNA | |
| SCHEMBL14845641 | 0.86 | MAPT (0.48) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL255485 | 0.86 | MAPT (0.44) | GPR119PIK3CAMAPTALDH1A1LMNA | |
| SCHEMBL29462384 | 0.85 | POLB (0.44) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL22650785 | 0.85 | POLB (0.44) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL29491170 | 0.82 | MAPT (0.51) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL255156 | 0.82 | MAPT (0.51) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL1665532 | 0.82 | ALDH1A1 (0.53) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL2120938 | 0.82 | GPR119 (0.64) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30947672 | 0.82 | GPR119 (0.64) | GPR119MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |