Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.49 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.48 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876241 | 0.88 | EPHX2 (0.49) | HPGDSMCHR1HTR2CEPHX2DDR1 | |
| SCHEMBL13876225 | 0.85 | EPHX2 (0.59) | HPGDSMCHR1HTR2CEPHX2DDR1 | |
| SCHEMBL16495961 | 0.83 | HPGDS (0.57) | HPGDSMCHR1HTR2CEPHX2PRKAA2 | |
| SCHEMBL16495368 | 0.82 | HPGDS (0.59) | HPGDS | |
| SCHEMBL16496198 | 0.81 | HPGDS (0.55) | HPGDSMCHR1HTR2C | |
| SCHEMBL16496094 | 0.81 | ROCK2 (0.58) | HPGDSMCHR1HTR2CEPHX2DGAT2 | |
| SCHEMBL13876240 | 0.81 | EPHX2 (0.51) | EPHX2DDR1 | |
| SCHEMBL16495583 | 0.80 | HPGDS (0.56) | HPGDSMCHR1HTR2C | |
| SCHEMBL13876691 | 0.80 | EPHX2 (0.61) | HPGDSMCHR1HTR2CEPHX2 | |
| SCHEMBL16495631 | 0.80 | HPGDS (0.67) | HPGDSMCHR1HTR2CPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
| WO-2007098352-A2 | SUBSTITUTED PYRIDINEAMIDE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, NCEH1 | HPGDS 29/4885MCHR1 4710/4885HTR2C 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.