Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 2/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876371 | 0.90 | LIPE (0.54) | LIPEEPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL14457026 | 0.86 | GRM5 (0.50) | LIPEEPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL13876984 | 0.86 | TRPV1 (0.55) | EPHX2TRPV1 | |
| SCHEMBL13876376 | 0.86 | EPHX2 (0.54) | EPHX2CYP2C9CYP2C19CYP2J2LMNA | |
| SCHEMBL13876388 | 0.85 | GCGR (0.52) | EPHX2GRM5PPARDTRPV1SCD | |
| SCHEMBL13876815 | 0.84 | EPHX2 (0.49) | EPHX2LMNATRPV1 | |
| SCHEMBL14456723 | 0.83 | GRM5 (0.50) | LIPEEPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL13876381 | 0.83 | GRM5 (0.52) | EPHX2GRM5OPRM1OPRD1OPRK1 | |
| SCHEMBL13876362 | 0.83 | EPHX2 (0.55) | EPHX2GRM5OPRM1OPRD1OPRK1 | |
| SCHEMBL4178518 | 0.81 | EPHX2 (0.73) | EPHX2CYP2C9CYP2C19CYP2J2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, NCEH1 | LIPE 634/4885EPHX2 2/4885CYP2C9 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.