Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876359 | 0.88 | EPHX2 (0.48) | EPHX2HPGDGRM5OPRM1OPRD1 | |
| SCHEMBL14457026 | 0.86 | GRM5 (0.50) | EPHX2HPGDGRM5OPRM1OPRD1 | |
| SCHEMBL14456723 | 0.83 | GRM5 (0.50) | EPHX2GRM5OPRM1OPRD1OPRK1 | |
| SCHEMBL13876367 | 0.83 | LIPE (0.51) | EPHX2GRM5OPRM1OPRD1OPRK1 | |
| SCHEMBL13876381 | 0.83 | GRM5 (0.52) | EPHX2GRM5OPRM1OPRD1OPRK1 | |
| SCHEMBL13876356 | 0.81 | GRM5 (0.50) | EPHX2GRM5OPRM1OPRD1OPRK1 | |
| SCHEMBL14457029 | 0.79 | EPHX2 (0.46) | EPHX2OPRM1OPRD1OPRK1HTT | |
| SCHEMBL13876535 | 0.77 | EPHX2 (0.70) | EPHX2OPRM1OPRD1OPRK1 | |
| SCHEMBL14456994 | 0.77 | EPHX2 (0.66) | EPHX2OPRM1OPRD1OPRK1PRKAA2 | |
| SCHEMBL6685808 | 0.77 | OPRM1 (0.54) | OPRM1OPRD1OPRK1GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885HPGD 14/4885GRM5 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.