Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876392 | 0.88 | SCN10A (0.61) | SCN10ANPC1RAB9ASMN1; SMN2XDH | |
| SCHEMBL13876805 | 0.87 | SMN1; SMN2 (0.51) | SCN10ANPC1RAB9ASMN1; SMN2XDH | |
| SCHEMBL13876849 | 0.87 | HDAC1 (0.61) | SCN10ANPC1RAB9ASMN1; SMN2XDH | |
| SCHEMBL14640423 | 0.85 | RAB9A (0.55) | SCN10ANPC1RAB9ASMN1; SMN2XDH | |
| SCHEMBL13876813 | 0.84 | RAB9A (0.51) | SCN10ANPC1RAB9ASMN1; SMN2XDH | |
| SCHEMBL12191059 | 0.82 | SCN10A (0.56) | SCN10ASMN1; SMN2USP30ULK1HDAC1 | |
| SCHEMBL13876806 | 0.82 | CTSA (0.55) | NPC1RAB9ASMN1; SMN2HDAC1HTT | |
| SCHEMBL13876390 | 0.80 | SMN1; SMN2 (0.51) | SCN10ANPC1RAB9ASMN1; SMN2SCN2A | |
| SCHEMBL10099572 | 0.79 | SMN1; SMN2 (0.67) | NPC1RAB9ASMN1; SMN2EPHX2HTT | |
| SCHEMBL13876809 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2HDAC1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-16 | — | — | US | disclosed |
| WO-2007098352-A2 | SUBSTITUTED PYRIDINEAMIDE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099184-A1 | Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, NCEH1 | SCN10A 3369/4885NPC1 1396/4885RAB9A 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.