Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.40 |
| ▸ | TK2 | O00142 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14528806 | 0.88 | TK1 (0.40) | TK1TK2HPGD | |
| SCHEMBL5158820 | 0.88 | TK1 (0.37) | TK1TK2HPGD | |
| SCHEMBL13890775 | 0.86 | KMT2A (0.39) | TK1TK2HPGD | |
| SCHEMBL18788917 | 0.85 | HPGD (0.40) | TK1TK2HPGD | |
| SCHEMBL7529489 | 0.82 | HPGD (0.43) | TK1HPGD | |
| SCHEMBL13660676 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL5097379 | 0.81 | HPGD (0.42) | TK1HPGD | |
| SCHEMBL8642052 | 0.80 | TK1 (0.39) | TK1TK2 | |
| SCHEMBL5360321 | 0.78 | TK1 (0.38) | TK1TK2HPGD | |
| SCHEMBL5175003 | 0.78 | KMT2A (0.40) | TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090104633-A1 | Kit for Highly Sensitive Detection Assays | VYZKUMNY USTAV VETERINARNIHO LEKARSTVI (CZ) | 2009-04-23 | — | — | US | disclosed |