SCHEMBL1387750

SCHEMBL1387750

N#Cc1ccc(N2C(=O)NC(=O)C2(CO)CO)cc1C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 15/20 0.54
PGR P06401 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387722 0.86 AR (0.58) ARPGR
SCHEMBL4023707 0.82 AR (0.73) ARPGR
SCHEMBL7759696 0.75 AR (0.67) ARPGR
SCHEMBL1387749 0.75 AR (0.70) ARPGR
SCHEMBL8177485 0.74 AR (0.59) ARPGR
SCHEMBL4052919 0.74 AR (0.56) ARPGR
SCHEMBL4032141 0.74 AR (0.61) ARPGR
SCHEMBL4022035 0.74 AR (0.65) ARPGR
SCHEMBL8213681 0.74 AR (0.64) ARPGR
SCHEMBL8174011 0.74 AR (0.61) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-H09507241-A 1997-07-22 JP claimed
EP-0738263-A1 NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1996-10-23 EP claimed
WO-1995018794-A1 NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1995-07-13 WO claimed
EP-0738263-A1 NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1996-10-23 EP disclosed
WO-1995018794-A1 NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1995-07-13 WO disclosed