SCHEMBL4023707

SCHEMBL4023707

CC1(C)C(=O)NC(=O)N1c1ccc(C#N)c(C(F)(F)F)c1

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 11/20 0.73
PGR P06401 1/20 0.51
ABCG2 Q9UNQ0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4032141 0.88 AR (0.61) ARPGRABCG2
SCHEMBL4022035 0.88 AR (0.65) ARPGRABCG2
SCHEMBL1387722 0.85 AR (0.58) ARPGRABCG2
SCHEMBL629858 0.84 AR (1.00) ARPGR
SCHEMBL4052919 0.83 AR (0.56) ARPGRABCG2
SCHEMBL1387750 0.82 AR (0.54) ARPGR
SCHEMBL4032142 0.81 AR (0.80) ARPGR
Acetic Acid SCHEMBL7784177 0.79 AR (0.89) ARPGR
SCHEMBL13185084 0.79 AR (0.52) AR
SCHEMBL23080486 0.79 AR (0.66) ARPGRABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009097996-A1 USE OF SUBSTITUTED PHENYLIMIDAZOLIDINES FOR PRODUCING MEDICAMENTS FOR TREATING METABOLIC SYNDROME SANOFI-AVENTIS (FR) 2009-08-13 WO disclosed
EP-0877738-A1 NEW PROCESS FOR THE PREPARATION OF PHENYLIMIDAZOLIDINE DERIVATIVES HOECHST MARION ROUSSEL (FR) 1998-11-18 EP disclosed
WO-1997018197-A1 NEW PROCESS FOR THE PREPARATION OF PHENYLIMIDAZOLIDINE DERIVATIVES HOECHST MARION ROUSSEL (FR) 1997-05-22 WO disclosed