SCHEMBL13879196

SCHEMBL13879196

Cc1ccc(-c2ccc(N(c3ccccc3)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.52
BCL2L1 Q07817 1/20 0.52
ACHE P22303 1/20 0.50
ESR1 P03372 7/20 0.42
ESR2 Q92731 2/20 0.42
LTB4R2 Q9NPC1 1/20 0.42
CYP2C19 P33261 3/20 0.42
MAPT P10636 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23789720 1.00 MMP3 (0.52) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL8279198 1.00 MMP3 (0.52) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL8279203 1.00 MMP3 (0.52) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL22182772 0.96 MMP3 (0.58) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL14173660 0.96 MMP3 (0.58) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL23789718 0.96 MMP3 (0.58) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL8178201 0.94 ACHE (0.56) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL12144279 0.92 ACHE (0.59) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL14173656 0.92 ACHE (0.59) MMP3BCL2L1ACHEESR1ESR2
SCHEMBL2609817 0.92 ACHE (0.59) MMP3BCL2L1ACHEESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7517625-B2 Electrophotographic photoreceptor with improved durability and wear resistance; high quality latent images; crosslinked charge transport layer has a hardened monomer having three or more functional groups without charge transport structure and one with charge transport-containing (meth)acryloyloxy groups RICOH COMPANY, LTD. (JP) 2009-04-14 US disclosed