Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | G6PC1 | P35575 | 5/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12572177 | 0.85 | MEN1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10865266 | 0.84 | MEN1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10938038 | 0.84 | MEN1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14254906 | 0.84 | MEN1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8494526 | 0.84 | MAPT (0.57) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8494529 | 0.84 | MAPT (0.57) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4885008 | 0.83 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4748290 | 0.83 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6300697 | 0.82 | ALDH1A1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6300692 | 0.82 | ALDH1A1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517625-B2 | Electrophotographic photoreceptor with improved durability and wear resistance; high quality latent images; crosslinked charge transport layer has a hardened monomer having three or more functional groups without charge transport structure and one with charge transport-containing (meth)acryloyloxy groups | RICOH COMPANY, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-7517625-B2 | Electrophotographic photoreceptor with improved durability and wear resistance; high quality latent images; crosslinked charge transport layer has a hardened monomer having three or more functional groups without charge transport structure and one with charge transport-containing (meth)acryloyloxy groups | RICOH COMPANY, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |