Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879519 | 0.71 | TAS2R8 (0.43) | TAS2R8BRD4 | |
| SCHEMBL1279274 | 0.71 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL13879562 | 0.69 | TAS2R8 (0.60) | TAS2R8BRD4 | |
| SCHEMBL13879435 | 0.67 | TAS2R8 (0.63) | TAS2R8LMNABRD4 | |
| SCHEMBL13879586 | 0.67 | TAS2R8 (0.50) | TAS2R8BRD4 | |
| SCHEMBL13879469 | 0.62 | LMNA (0.75) | TAS2R8LMNA | |
| SCHEMBL13879570 | 0.62 | KMT2A (0.41) | LMNA | |
| SCHEMBL13879463 | 0.61 | LMNA (0.52) | TAS2R8LMNA | |
| SCHEMBL13879407 | 0.61 | KMT2A (0.37) | TAS2R8BRD4 | |
| SCHEMBL13592894 | 0.61 | LMNA (0.40) | TAS2R8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| WO-2007047146-A2 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | TAS2R8 4662/4885LMNA 2024/4885BRD4 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.