Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.93 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.93 |
| ▸ | TNF | P01375 | 3/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | TACR1 | P25103 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528722 | 0.92 | TNF (1.00) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL5531669 | 0.91 | L3MBTL1 (1.00) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL838180 | 0.85 | KMT2A (0.75) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL17830374 | 0.83 | TNF (0.82) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL25154850 | 0.82 | KMT2A (0.69) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL7827097 | 0.81 | KMT2A (0.68) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL7815529 | 0.81 | KMT2A (0.68) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL4287307 | 0.81 | HDAC1 (0.75) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL7822959 | 0.81 | HDAC1 (0.75) | KMT2AMEN1L3MBTL1TNFMAPT | |
| SCHEMBL11639246 | 0.80 | NPSR1 (0.73) | KMT2AMEN1L3MBTL1TNFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | KMT2A 2463/4885MEN1 4395/4885L3MBTL1 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.