Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.59 |
| ▸ | ITGAL | P20701 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879681 | 0.88 | ITGB2 (0.51) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL13879623 | 0.87 | ITGB2 (0.57) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL4280125 | 0.80 | ALDH1A1 (0.58) | ITGB2ICAM1ITGALALDH1A1NAMPT | |
| SCHEMBL4280119 | 0.80 | ALDH1A1 (0.58) | ITGB2ICAM1ITGALALDH1A1NAMPT | |
| SCHEMBL13879615 | 0.80 | GAA (0.52) | ITGB2ICAM1ITGALALDH1A1MAPK1 | |
| SCHEMBL13879617 | 0.78 | ITGB2 (0.60) | ITGB2ICAM1ITGALHSD17B10LMNA | |
| SCHEMBL15854246 | 0.76 | ALDH1A1 (0.52) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL15854225 | 0.76 | ALDH1A1 (0.63) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL17219360 | 0.76 | ALDH1A1 (0.52) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL13879614 | 0.75 | CYP3A4 (0.64) | ALDH1A1MAPK1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | ITGB2 4487/4885ICAM1 2947/4885ITGAL 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.