Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 4/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.48 |
| ▸ | ITGAL | P20701 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15854246 | 1.00 | ALDH1A1 (0.52) | ALDH1A1NAMPTITGB2ICAM1ITGAL | |
| SCHEMBL15854258 | 0.92 | ALDH1A1 (0.53) | ALDH1A1NAMPTITGB2ICAM1ITGAL | |
| SCHEMBL17219316 | 0.92 | ALDH1A1 (0.53) | ALDH1A1NAMPTITGB2ICAM1ITGAL | |
| SCHEMBL15854245 | 0.86 | ITGB2 (0.54) | ALDH1A1NAMPTITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL17219103 | 0.85 | ITGB2 (0.53) | ALDH1A1NAMPTITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL17219099 | 0.85 | ITGB2 (0.53) | ALDH1A1NAMPTITGB2ICAM1ITGAL | |
| SCHEMBL15854225 | 0.80 | ALDH1A1 (0.63) | ALDH1A1ITGB2ICAM1ITGALPOLB | |
| Hydrochloric Acid SCHEMBL17219644 | 0.79 | ALDH1A1 (0.62) | ALDH1A1ITGB2ICAM1ITGALPOLB | |
| Hydrochloric Acid SCHEMBL17219646 | 0.79 | ALDH1A1 (0.62) | ALDH1A1ITGB2ICAM1ITGALPOLB | |
| SCHEMBL17219569 | 0.76 | ITGB2 (0.53) | ALDH1A1ITGB2ICAM1ITGALKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540338-B2 | Substituted cinnamic acid amides for treating pain | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-20150322024-A1 | Cinnamic Acid Amide Derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-2940003-A1 | CINNAMIC ACID AMIDE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322024-A1 | Cinnamic Acid Amide Derivative | OPRL1, TRPV1, TRPA1 | ALDH1A1 350/4885NAMPT 937/4885ITGB2 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.