Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998375 | 0.81 | TRPV1 (0.52) | TRPV1RAB9ANPC1HPGDPOLB | |
| SCHEMBL4870194 | 0.78 | TRPV1 (0.49) | TRPV1RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL25046252 | 0.75 | RAB9A (0.69) | RAB9ANPC1HPGDALDH1A1POLB | |
| SCHEMBL9311053 | 0.75 | TRPV1 (0.42) | TRPV1HPGDALDH1A1POLBKMT2A | |
| SCHEMBL3365956 | 0.74 | ALDH1A1 (0.44) | TRPV1HPGDALDH1A1POLBKMT2A | |
| SCHEMBL8175962 | 0.73 | RAB9A (0.46) | TRPV1RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL14027406 | 0.72 | MAPT (0.44) | TRPV1HPGDALDH1A1KMT2AL3MBTL1 | |
| Sulfuric Acid SCHEMBL9311042 | 0.72 | TRPV1 (0.41) | TRPV1HPGDALDH1A1POLBKMT2A | |
| SCHEMBL9687520 | 0.71 | ALDH1A1 (0.61) | RAB9ANPC1HPGDALDH1A1POLB | |
| SCHEMBL14003063 | 0.71 | TRPV1 (0.43) | TRPV1HPGDALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |