Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.35 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321186 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTALOX15LMNA | |
| SCHEMBL8849510 | 0.58 | ALDH1A1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL19193446 | 0.56 | CA2 (0.36) | ALDH1A1SMN1; SMN2KDM4ECYP1A2MAPT | |
| SCHEMBL18027480 | 0.52 | — | — | |
| SCHEMBL13015646 | 0.51 | — | — | |
| SCHEMBL13410856 | 0.48 | — | — | |
| SCHEMBL39492 | 0.47 | — | — | |
| Tert-Butanol SCHEMBL282 | 0.47 | — | — | |
| Tert-Butanol SCHEMBL20503401 | 0.47 | ALDH1A1 (0.46) | ALDH1A1LMNATSHR | |
| Tert-Butanol SCHEMBL788666 | 0.47 | ALDH1A1 (0.46) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090087376-A1 | Heterocyclic Dye Compounds For In Vivo Imaging And Diagnosis Of Alzheimer's Disease | THE GENERAL HOSPITAL CORPORATION (US) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087376-A1 | Heterocyclic Dye Compounds For In Vivo Imaging And Diagnosis Of Alzheimer's Disease | APP, PSEN1, BACE1 | ALDH1A1 317/4885SMN1; SMN2 436/4885KDM4E 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.