Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.33 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.33 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880864 | 0.93 | THRB (0.34) | THRBCYP1A2ENPP2MEN1KMT2A | |
| SCHEMBL13880942 | 0.88 | THRB (0.41) | THRBCYP1A2ENPP2CA2CA3 | |
| SCHEMBL13880947 | 0.86 | THRB (0.53) | THRBCYP1A2ENPP2CA2CA3 | |
| SCHEMBL13880963 | 0.85 | THRB (0.37) | THRBCYP1A2ENPP2CA2CA3 | |
| SCHEMBL13880961 | 0.85 | THRB (0.36) | THRBENPP2CA2CA3MEN1 | |
| SCHEMBL13880958 | 0.84 | ENPP2 (0.39) | THRBCYP1A2ENPP2CA2CA3 | |
| SCHEMBL13880964 | 0.84 | ENPP2 (0.39) | THRBENPP2CA2CA3MEN1 | |
| SCHEMBL13880965 | 0.84 | THRB (0.36) | THRBENPP2CA2CA3 | |
| SCHEMBL13880821 | 0.82 | THRB (0.35) | THRBCYP1A2ENPP2HPGD | |
| SCHEMBL13880866 | 0.82 | THRB (0.33) | THRBENPP2MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090098074-A1 | Keratin-Binding Effector Molecules Containing Reactive Dyes | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090098074-A1 | Keratin-Binding Effector Molecules Containing Reactive Dyes | KRT18, KLK3, KLKB1 | THRB 3581/4885CYP1A2 4054/4885ENPP2 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.