Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19291673 | 0.88 | CYP2D6 (0.41) | BCHENOS1NOS2ACHECYP2D6 | |
| SCHEMBL13881782 | 0.88 | PRMT5 (0.38) | ACHECYP2D6PPARGPPARA | |
| SCHEMBL20332390 | 0.87 | TAAR1 (0.43) | BCHEACHECYP2D6PPARGPPARA | |
| SCHEMBL2208855 | 0.87 | TAAR1 (0.45) | BCHEACHECYP2D6PPARGPPARA | |
| SCHEMBL2204946 | 0.84 | TAAR1 (0.47) | BCHEACHECYP2D6PPARGPPARA | |
| SCHEMBL13881576 | 0.82 | BCHE (0.42) | BCHECYP2D6PPARGPPARA | |
| SCHEMBL13881712 | 0.81 | ALDH1A1 (0.38) | NOS1NOS2TAAR1 | |
| SCHEMBL20318730 | 0.78 | PPARA (0.49) | BCHECYP2D6PPARGPPARA | |
| SCHEMBL4568761 | 0.78 | PPARA (0.51) | BCHECYP2D6PPARGPPARA | |
| SCHEMBL4568762 | 0.77 | PPARA (0.52) | BCHECYP2D6PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |