Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389117 | 0.89 | CNR1 (0.41) | CNR1CNR2F10PRSS1NPY1R | |
| SCHEMBL9268570 | 0.89 | CNR1 (0.41) | CNR1CNR2EPHX2NPY1R | |
| SCHEMBL9276101 | 0.86 | CNR1 (0.39) | CNR1CNR2EPHX2NPY1R | |
| SCHEMBL9195777 | 0.84 | CNR1 (0.32) | CNR1NPY1R | |
| SCHEMBL1388355 | 0.83 | TDP1 (0.37) | CNR1CNR2NPY1R | |
| SCHEMBL9202531 | 0.83 | MEN1 (0.38) | CNR1F10PRSS1NPY1R | |
| SCHEMBL9200886 | 0.82 | TPSAB1 (0.39) | CNR1NPY1R | |
| SCHEMBL9200988 | 0.82 | CYP2C9 (0.38) | CNR1F10EPHX2NPY1RGAA | |
| SCHEMBL4650866 | 0.81 | NPY1R (0.42) | CNR1CNR2NPY1R | |
| SCHEMBL1388287 | 0.81 | CNR1 (0.45) | CNR1CNR2F10PRSS1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H08505862-A | — | — | 1996-06-25 | — | — | JP | claimed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | claimed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | claimed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |