Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 10/20 | 0.42 |
| ▸ | NPY4R | P50391 | 11/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.41 |
| ▸ | NPY2R | P49146 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389117 | 0.91 | CNR1 (0.41) | NPY1RNPY4RNPY5RNPY2RCNR1 | |
| SCHEMBL1388355 | 0.89 | TDP1 (0.37) | NPY1RNPY4RNPY5RNPY2RCNR1 | |
| SCHEMBL9200886 | 0.88 | TPSAB1 (0.39) | NPY1RNPY4RNPY5RNPY2RCNR1 | |
| SCHEMBL9202531 | 0.86 | MEN1 (0.38) | NPY1RNPY4RNPY5RNPY2RCNR1 | |
| SCHEMBL9200988 | 0.86 | CYP2C9 (0.38) | NPY1RCNR1 | |
| SCHEMBL6901610 | 0.86 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL9203837 | 0.85 | F2 (0.38) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL4650863 | 0.83 | NPY1R (0.40) | NPY1RNPY4RNPY5RNPY2RCNR1 | |
| SCHEMBL9271799 | 0.82 | CNR1 (0.35) | NPY1RNPY4RNPY5RNPY2RCNR1 | |
| SCHEMBL9276101 | 0.81 | CNR1 (0.39) | NPY1RCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |