Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 14/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975861 | 1.00 | ALDH1A1 (0.54) | ALDH1A1ALOX5APMMP2MMP13DRD4 | |
| SCHEMBL12920642 | 0.91 | ALOX5AP (0.53) | ALOX5APDRD4 | |
| SCHEMBL975396 | 0.91 | ALOX5AP (0.53) | ALOX5APDRD4 | |
| SCHEMBL977088 | 0.90 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL977086 | 0.90 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL12920645 | 0.89 | ALOX5AP (0.51) | ALOX5APDRD4 | |
| SCHEMBL976578 | 0.89 | ALOX5AP (0.51) | ALDH1A1ALOX5APDRD4 | |
| SCHEMBL12920644 | 0.89 | ALOX5AP (0.51) | ALDH1A1ALOX5APDRD4 | |
| SCHEMBL12948062 | 0.88 | ALOX5AP (0.51) | ALOX5APDRD4 | |
| SCHEMBL976621 | 0.88 | ALOX5AP (0.57) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048547-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. (US) | 2009-04-16 | — | — | WO | disclosed |