Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 14/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920642 | 1.00 | ALOX5AP (0.53) | ALOX5APSLC6A5DRD4 | |
| SCHEMBL977088 | 0.92 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL977086 | 0.92 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL12920645 | 0.92 | ALOX5AP (0.51) | ALOX5APSLC6A5DRD4 | |
| SCHEMBL12920644 | 0.92 | ALOX5AP (0.51) | ALOX5APDRD4 | |
| SCHEMBL976578 | 0.92 | ALOX5AP (0.51) | ALOX5APDRD4 | |
| SCHEMBL12948062 | 0.91 | ALOX5AP (0.51) | ALOX5APDRD4 | |
| SCHEMBL976620 | 0.91 | ALOX5AP (0.57) | ALOX5AP | |
| SCHEMBL976621 | 0.91 | ALOX5AP (0.57) | ALOX5AP | |
| SCHEMBL13883137 | 0.91 | ALDH1A1 (0.54) | ALOX5APDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | PTGIS, PTGS1, LTC4S | ALOX5AP 47/4885SLC6A5 4736/4885DRD4 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.