Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | LMNA | P02545 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909361 | 0.95 | CTSS (0.63) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL608154 | 0.90 | CTSS (0.58) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL608153 | 0.90 | CTSS (0.58) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL8909541 | 0.90 | KMT2A (0.57) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL8909400 | 0.90 | MAPT (0.57) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL13882993 | 0.90 | KMT2A (0.57) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL8908902 | 0.88 | CTSS (0.58) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL8908931 | 0.88 | CTSS (0.58) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL8910405 | 0.88 | CTSS (0.57) | CTSSCTSKMAPTLMNAKMT2A | |
| SCHEMBL8910056 | 0.87 | MAPT (0.59) | CTSSCTSKMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048750-A2 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-16 | — | — | WO | disclosed |