Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608153 | 1.00 | CTSS (0.58) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8909361 | 0.95 | CTSS (0.63) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8910056 | 0.92 | MAPT (0.59) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL13883261 | 0.90 | CTSS (0.60) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8908257 | 0.90 | CTSS (0.54) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8909076 | 0.89 | KMT2A (0.56) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8908952 | 0.88 | KMT2A (0.51) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8908922 | 0.86 | KMT2A (0.56) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8909766 | 0.86 | MAPT (0.59) | CTSSCTSKKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8908971 | 0.85 | CTSS (0.52) | CTSSCTSKKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2481730-B1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2013-12-18 | — | — | EP | disclosed |
| EP-2481731-B1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2197857-B1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2481730-A1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | Dow AgroSciences LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2481731-A1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | Dow AgroSciences LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-8188273-B2 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES, LLC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2012-02-16 | — | — | US | disclosed |
| US-8067588-B2 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2011-11-29 | — | — | US | disclosed |
| US-20090093481-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093481-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | HELZ, API5, CRYZ | CTSS 2670/4885CTSK 893/4885KMT2A 1091/4885 |
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | HELZ, API5, CRYZ | CTSS 2670/4885CTSK 893/4885KMT2A 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.