Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407873 | 0.78 | CCR3 (0.65) | — | |
| SCHEMBL13389790 | 0.78 | CCR3 (0.65) | — | |
| SCHEMBL29816208 | 0.78 | TDP1 (0.68) | POLBKMT2AMEN1MAPK1CYP2C9 | |
| SCHEMBL31238166 | 0.73 | ALDH1A1 (0.70) | POLBKMT2AMEN1MAPK1CYP2C9 | |
| SCHEMBL1809205 | 0.72 | POLB (0.51) | POLBKMT2AMEN1MAPK1CYP2C9 | |
| SCHEMBL1811001 | 0.72 | POLB (0.53) | POLBKMT2AMEN1MAPK1HTR3E | |
| SCHEMBL29699346 | 0.71 | ALDH1A1 (0.60) | POLBKMT2AMEN1MAPK1TDP1 | |
| SCHEMBL6184046 | 0.71 | ACACB (0.66) | POLBMAPK1CYP2C9RAB9ATDP1 | |
| SCHEMBL24183460 | 0.69 | SMN1; SMN2 (0.57) | KMT2AMEN1CYP2C9RAB9ANPSR1 | |
| SCHEMBL29787263 | 0.69 | SMN1; SMN2 (0.57) | KMT2AMEN1CYP2C9RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725235-B1 | PIPERIDINE DERIVATIVES USEFUL AS CCR3 ANTAGONISTS | SCHERING CORP (US) | 2009-04-15 | — | — | EP | disclosed |