Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816208 | 0.86 | TDP1 (0.68) | KDM4EMAPK1POLBMEN1KMT2A | |
| SCHEMBL28206921 | 0.80 | KDM4E (0.92) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL27306048 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL2016229 | 0.76 | MEN1 (0.63) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL28857503 | 0.76 | KDM4E (0.76) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL1811001 | 0.76 | POLB (0.53) | ALDH1A1KDM4ELMNAGAAMAPK1 | |
| SCHEMBL25138718 | 0.76 | KDM4E (1.00) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL5534950 | 0.76 | KDM4E (0.89) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL18854912 | 0.75 | KMT2A (0.66) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL17171763 | 0.75 | RAB9A (0.47) | ALDH1A1KDM4ELMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |