Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19677064 | 0.68 | — | — | |
| SCHEMBL21676593 | 0.66 | CYP3A4 (0.39) | TSHRTDP1 | |
| SCHEMBL15581118 | 0.65 | ACHE (0.40) | TSHRTDP1 | |
| SCHEMBL20692528 | 0.64 | CYP1A2 (0.33) | — | |
| SCHEMBL24158773 | 0.63 | ADORA2A (0.35) | — | |
| SCHEMBL22276384 | 0.63 | — | — | |
| SCHEMBL22591067 | 0.63 | MAPT (0.30) | — | |
| SCHEMBL23230384 | 0.62 | PKM (0.40) | TSHR | |
| SCHEMBL3267220 | 0.62 | KMT2A (0.56) | TSHR | |
| SCHEMBL15751163 | 0.61 | TSHR (0.47) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514441-B2 | Substituted pyrazolo [1,5-A]pyrimidines as calcium receptor modulating agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-07 | — | — | US | disclosed |