Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8121834 | 0.99 | F10 (0.43) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL8525704 | 0.90 | F10 (0.44) | F10PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8119799 | 0.90 | EPHX1 (0.45) | PRSS1PRSS2PRSS3NR1H3EPHX1 | |
| SCHEMBL6900983 | 0.89 | PRSS1 (0.41) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL8119473 | 0.89 | NR1H3 (0.46) | NR1H3EPHX1TDP1ACHEMEN1 | |
| SCHEMBL7058207 | 0.89 | PRSS1 (0.41) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL1389096 | 0.88 | F10 (0.43) | F10PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8122656 | 0.88 | PRSS1 (0.40) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL8526150 | 0.88 | PLAU (0.41) | F10PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8121985 | 0.86 | NR1H3 (0.41) | NR1H3EPHX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| JP-H08505862-A | — | — | 1996-06-25 | — | — | JP | claimed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | claimed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | claimed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |