Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 12/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | GLI1 | P08151 | 1/20 | 0.37 |
| ▸ | GLI2 | P10070 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900983 | 1.00 | PRSS1 (0.41) | PRSS1PRSS2PRSS3F10TRPM8 | |
| Hydrochloric Acid SCHEMBL8122656 | 0.99 | PRSS1 (0.40) | PRSS1PRSS2PRSS3F10TRPM8 | |
| SCHEMBL8121716 | 0.92 | SLC6A4 (0.43) | TRPM8GLI1GLI2MEN1KMT2A | |
| SCHEMBL8526150 | 0.91 | PLAU (0.41) | PRSS1PRSS2PRSS3F10TRPM8 | |
| SCHEMBL1388852 | 0.90 | TPSAB1 (0.39) | PRSS1PRSS2PRSS3F10F2 | |
| Hydrochloric Acid SCHEMBL8112935 | 0.89 | TPSAB1 (0.38) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL1389004 | 0.89 | F10 (0.44) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL8526765 | 0.89 | F10 (0.45) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL8121972 | 0.88 | TRPM8 (0.38) | TRPM8GLI1GLI2PLAUMEN1 | |
| Hydrochloric Acid SCHEMBL8121834 | 0.88 | F10 (0.43) | PRSS1PRSS2PRSS3F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |