Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.77 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.76 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.76 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.76 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851843 | 1.00 | KCNH2 (0.77) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| SCHEMBL8759496 | 0.95 | KCNH2 (0.76) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| SCHEMBL8759491 | 0.95 | KCNH2 (0.76) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| Rapacuronium SCHEMBL16977930 | 0.94 | KCNH2 (0.71) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| SCHEMBL13851842 | 0.94 | KCNH2 (0.86) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| Bromide SCHEMBL8760594 | 0.94 | KCNH2 (0.75) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| Bromide SCHEMBL8760418 | 0.94 | KCNH2 (0.75) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| SCHEMBL13720309 | 0.94 | KCNH2 (0.86) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| Bromide SCHEMBL8760605 | 0.94 | KCNH2 (0.75) | KCNH2HRH3AGTR1SLC22A2SLC47A2 | |
| Rapacuronium SCHEMBL1650924 | 0.94 | SLC22A2 (0.71) | KCNH2HRH3AGTR1SLC22A2SLC47A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093632-A1 | Processes for the synthesis of rocuronium bromide | MENDEZ JUANA ARACELI | 2009-04-09 | — | — | US | disclosed |
| WO-2007033348-A2 | PROCESS FOR THE SYNTHESIS OF ROCURONIUM BROMIDE | SICOR, INC. (US) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093632-A1 | Processes for the synthesis of rocuronium bromide | HSD17B7, HSD3B2, HSD3B1 | KCNH2 1692/4885HRH3 3175/4885AGTR1 2139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.