Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28242170 | 0.85 | HSD17B10 (0.30) | — | |
| SCHEMBL18893469 | 0.79 | OPRM1 (0.42) | TSHR | |
| SCHEMBL18489546 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL12362044 | 0.77 | — | — | |
| SCHEMBL11911872 | 0.75 | — | — | |
| SCHEMBL11950509 | 0.75 | — | — | |
| SCHEMBL3482247 | 0.74 | TSHR (0.32) | TSHRMETAP1 | |
| SCHEMBL11991207 | 0.74 | CA2 (0.38) | TSHR | |
| SCHEMBL17834246 | 0.73 | METAP1 (0.32) | METAP1 | |
| SCHEMBL5831203 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787992-B1 | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-04-29 | — | — | EP | disclosed |