Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP5 | P51878 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891620 | 0.90 | TACR1 (0.43) | TACR1CASP1CASP5 | |
| SCHEMBL6508415 | 0.89 | TACR1 (0.44) | TACR1 | |
| SCHEMBL29373661 | 0.89 | TACR1 (0.44) | TACR1 | |
| SCHEMBL13891688 | 0.87 | TACR1 (0.41) | TACR1CASP1CASP5 | |
| SCHEMBL15680049 | 0.85 | TACR1 (0.41) | TACR1 | |
| SCHEMBL13891718 | 0.85 | TACR1 (0.40) | TACR1BRAFROCK2ROCK1 | |
| SCHEMBL13891760 | 0.83 | TACR1 (0.41) | TACR1ROCK2ROCK1 | |
| SCHEMBL13891689 | 0.83 | TACR1 (0.35) | TACR1ROCK2ROCK1 | |
| SCHEMBL13891717 | 0.82 | ADRB2 (0.43) | TACR1CASP1CASP5ROCK2ROCK1 | |
| SCHEMBL13891621 | 0.82 | TACR1 (0.38) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473295-B1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-01 | — | — | EP | disclosed |