Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891764 | 0.91 | PIK3R1 (0.38) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL13891705 | 0.91 | MTOR (0.38) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL13891704 | 0.89 | PIK3R1 (0.46) | PIK3R1MTORTACR1CASP1CASP5 | |
| SCHEMBL13891619 | 0.87 | MTOR (0.47) | PIK3R1MTORTACR1CASP1CASP5 | |
| SCHEMBL13891687 | 0.83 | PIK3R1 (0.41) | PIK3R1MTORTACR1CASP1CASP5 | |
| SCHEMBL13891741 | 0.82 | MTOR (0.46) | PIK3R1MTORTACR1CASP1CASP5 | |
| SCHEMBL13891719 | 0.82 | TACR1 (0.48) | TACR1CASP1CASP5ROCK2ROCK1 | |
| SCHEMBL6508415 | 0.81 | TACR1 (0.44) | PIK3R1MTORTACR1TSHR | |
| SCHEMBL29373661 | 0.81 | TACR1 (0.44) | PIK3R1MTORTACR1TSHR | |
| SCHEMBL13891688 | 0.81 | TACR1 (0.41) | TACR1CASP1CASP5TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473295-B1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-01 | — | — | EP | disclosed |