Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826270 | 0.89 | PYCR1 (0.55) | ACKR3SIGMAR1TMEM97PYCR1TAAR1 | |
| SCHEMBL25046697 | 0.84 | TAAR1 (0.58) | SIGMAR1TAAR1LTA4HAOC3 | |
| SCHEMBL21664511 | 0.83 | PYCR1 (0.53) | ACKR3SIGMAR1TMEM97PYCR1TAAR1 | |
| SCHEMBL14308432 | 0.83 | PYCR1 (0.50) | ACKR3SIGMAR1TMEM97PYCR1BCHE | |
| SCHEMBL5205808 | 0.81 | MAPT (0.49) | ACKR3SIGMAR1TMEM97BCHE | |
| SCHEMBL5744436 | 0.81 | SIGMAR1 (0.65) | ACKR3SIGMAR1TMEM97 | |
| SCHEMBL13989609 | 0.80 | PYCR1 (0.50) | ACKR3SIGMAR1TMEM97PYCR1TAAR1 | |
| SCHEMBL27083411 | 0.80 | PYCR1 (0.50) | ACKR3SIGMAR1TMEM97PYCR1TAAR1 | |
| Hydrochloric Acid SCHEMBL31687514 | 0.80 | PYCR1 (0.50) | ACKR3SIGMAR1TMEM97PYCR1TAAR1 | |
| SCHEMBL30093198 | 0.80 | PYCR1 (0.67) | PYCR1TAAR1L3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |
| EP-1473295-B1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-01 | — | — | EP | disclosed |