Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13141699 | 0.91 | TACR3 (0.49) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141708 | 0.88 | MAPT (0.50) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141680 | 0.82 | ALOX15 (0.54) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141793 | 0.81 | MAPT (0.48) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141675 | 0.81 | KDM4E (0.48) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141682 | 0.80 | MAPT (0.51) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL3086423 | 0.79 | MAPT (0.47) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141673 | 0.77 | MAPT (0.46) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141668 | 0.74 | HTR6 (0.46) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13141670 | 0.73 | CCNT1 (0.43) | MAPTALOX15SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051705-A1 | SUBSTITUTED 1,2,4-OXADIAZOLES AND ANALOGS THEREOF AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. (US) | 2009-04-23 | — | — | WO | disclosed |