Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718835 | 0.89 | KDM4E (0.35) | RAB9ATP53KDM4EHSD17B10MAPT | |
| SCHEMBL719674 | 0.84 | RAB9A (0.35) | RAB9ATP53KDM4EHSD17B10MAPT | |
| SCHEMBL720342 | 0.80 | TP53 (0.34) | RAB9ATP53KDM4EHSD17B10KMT2A | |
| SCHEMBL10286220 | 0.80 | ALDH1A1 (0.36) | RAB9ATP53KDM4EHSD17B10MAPT | |
| SCHEMBL16127118 | 0.77 | KDM4E (0.32) | RAB9AKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL29556168 | 0.77 | KDM4E (0.33) | RAB9AKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL16038100 | 0.77 | KDM4E (0.33) | RAB9AKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL12558646 | 0.77 | ALOX5AP (0.30) | — | |
| SCHEMBL10252070 | 0.76 | RAB9A (0.49) | RAB9ATP53KDM4EHSD17B10MAPT | |
| SCHEMBL10255571 | 0.76 | KDM4E (0.39) | RAB9ATP53KDM4EHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046090-A1 | 2-SUBSTITUTED-6-AMINO-5-ALKYL, ALKENYL OR ALKYNYL-4-PYRIMIDINECARBOXYLIC ACIDS AND 6-SUBSTITUTED-4-AMINO-3- ALKYL, ALKENYL OR ALKYNYL PICOLINIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | WO | disclosed |