Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 10/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678129 | 1.00 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL | |
| SCHEMBL9675596 | 1.00 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL | |
| SCHEMBL9675618 | 1.00 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL | |
| SCHEMBL10869113 | 1.00 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL | |
| SCHEMBL9677665 | 0.84 | REN (0.54) | CTSSCTSKBACE1REN | |
| SCHEMBL9677655 | 0.84 | REN (0.54) | CTSSCTSKBACE1REN | |
| SCHEMBL7828875 | 0.81 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL | |
| SCHEMBL11043050 | 0.81 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL | |
| SCHEMBL5411977 | 0.81 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL | |
| SCHEMBL11137675 | 0.81 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514408-B1 | β-secretase enzyme compositions and methods | ELAN PHARMACEUTICALS, INC. (US) | 2009-04-07 | — | — | US | disclosed |