Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | CTSE | P14091 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677655 | 1.00 | REN (0.54) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL10869113 | 0.84 | CA1 (0.54) | RENCTSSCTSKBACE1 | |
| SCHEMBL9675596 | 0.84 | CA1 (0.54) | RENCTSSCTSKBACE1 | |
| SCHEMBL9675618 | 0.84 | CA1 (0.54) | RENCTSSCTSKBACE1 | |
| SCHEMBL9678129 | 0.84 | CA1 (0.54) | RENCTSSCTSKBACE1 | |
| SCHEMBL13893333 | 0.84 | CA1 (0.54) | RENCTSSCTSKBACE1 | |
| SCHEMBL10754918 | 0.83 | KLK5 (0.49) | RENCTSSCTSK | |
| SCHEMBL10754923 | 0.83 | KLK5 (0.49) | RENCTSSCTSK | |
| SCHEMBL10754932 | 0.83 | KLK5 (0.49) | RENCTSSCTSK | |
| SCHEMBL9676607 | 0.83 | REN (0.43) | RENCTSDCTSECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4880781-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| US-4829072-A | BACTERICIDES, FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1989-05-09 | — | — | US | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |