Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910054 | 0.92 | LMNA (0.68) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6910053 | 0.92 | LMNA (0.68) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6909183 | 0.92 | LMNA (0.68) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6909186 | 0.92 | LMNA (0.68) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6910050 | 0.92 | LMNA (0.68) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3846512 | 0.88 | ALDH1A1 (0.84) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6905580 | 0.88 | ALDH1A1 (0.84) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6908933 | 0.88 | ALDH1A1 (0.84) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3846508 | 0.88 | ALDH1A1 (0.84) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6907927 | 0.88 | ALDH1A1 (0.84) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350453-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2014-11-27 | — | — | US | disclosed |
| US-8632565-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2014-01-21 | — | — | US | disclosed |
| US-20130230472-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130165970-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WTH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-7514399-B2 | Use in tissue bonding and protein cross-linking and use in tissue and arterial repair, preservation of expanded internal luminal diameters, and local delivery of drugs, skin care materials, sunscreens, and cosmetics | PHOTOBIOMED CORPORATION (US) | 2009-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350453-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, TAGLN2, DCLRE1A | LMNA 436/4885ALDH1A1 1245/4885CYP3A4 3810/4885 |
| US-20130230472-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, TAGLN2, DCLRE1A | LMNA 436/4885ALDH1A1 1245/4885CYP3A4 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.