Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894352 | 0.94 | PTGER1 (0.62) | PTGER1THRBALDH1A1LMNAHPGD | |
| SCHEMBL13894128 | 0.94 | PTGER1 (0.62) | PTGER1THRBALDH1A1LMNAHPGD | |
| SCHEMBL13894121 | 0.91 | PTGER1 (0.60) | PTGER1THRBSMN1; SMN2 | |
| SCHEMBL13894311 | 0.90 | PTGER1 (0.58) | PTGER1THRBALDH1A1LMNAHPGD | |
| SCHEMBL12487799 | 0.88 | PTGER1 (0.65) | PTGER1SMN1; SMN2 | |
| SCHEMBL12481864 | 0.88 | PTGER1 (0.59) | PTGER1THRBRORC | |
| SCHEMBL12487481 | 0.87 | PTGER1 (0.59) | PTGER1THRBALDH1A1LMNAHPGD | |
| SCHEMBL13894479 | 0.87 | LMNA (0.62) | PTGER1THRBALDH1A1LMNAHPGD | |
| SCHEMBL12482129 | 0.86 | PTGER1 (0.58) | PTGER1THRBALDH1A1LMNAHPGD | |
| SCHEMBL13894296 | 0.86 | PTGER1 (0.58) | PTGER1THRBLMNARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050446-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-04-22 | — | — | EP | disclosed |