Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 4/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12484938 | 0.91 | RORC (0.59) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL12481964 | 0.91 | RORC (0.61) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL13894138 | 0.89 | RORC (0.57) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL12486938 | 0.89 | RORC (0.57) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL12482347 | 0.88 | RORC (0.56) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL13894303 | 0.87 | RORC (0.54) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL13894483 | 0.87 | PTGER1 (0.66) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL12487799 | 0.86 | PTGER1 (0.65) | SMN1; SMN2PTGER1MEN1KMT2ATP53 | |
| SCHEMBL12407696 | 0.86 | LMNA (0.64) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL12481864 | 0.85 | PTGER1 (0.59) | RORCPTGER1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050446-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-04-22 | — | — | EP | disclosed |