Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 19/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 8/20 | 0.62 |
| ▸ | DRD2 | P14416 | 5/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666784 | 0.86 | DRD4 (0.66) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27645338 | 0.83 | DRD4 (0.66) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9385194 | 0.83 | DRD4 (0.78) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11973909 | 0.82 | DRD4 (0.76) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7262675 | 0.82 | DRD4 (0.76) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7371617 | 0.82 | DRD4 (0.76) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4690091 | 0.81 | DRD4 (0.71) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4316173 | 0.81 | DRD4 (0.66) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL735729 | 0.80 | DRD4 (0.73) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7696047 | 0.80 | DRD4 (0.73) | DRD4CYP2D6CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524852-B2 | Bicyclic pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |