Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895478 | 1.00 | TSHR (0.36) | TSHRALDH1A1TDP1CA12CA1 | |
| SCHEMBL6140903 | 0.95 | — | — | |
| SCHEMBL21087406 | 0.83 | TSHR (0.34) | TSHR | |
| SCHEMBL17689173 | 0.82 | TSHR (0.45) | TSHR | |
| SCHEMBL15803984 | 0.80 | TSHR (0.48) | TSHRALDH1A1 | |
| SCHEMBL17401248 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL9945700 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL9945703 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL22589673 | 0.80 | TSHR (0.48) | TSHRALDH1A1 | |
| SCHEMBL12360400 | 0.80 | TSHR (0.48) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017527-B2 | KLK4 inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2018-07-10 | — | — | US | disclosed |
| EP-3049426-B1 | GLYCOCLUSTERS AND THEIR PHARMACEUTICAL USE AS ANTIBACTERIALS | CENTRE NAT RECH SCIENT (FR) | 2017-11-01 | — | — | EP | disclosed |
| US-20170101427-A1 | NOVEL KLK4 INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2017-04-13 | — | — | US | disclosed |
| WO-2015144933-A1 | NOVEL KLK4 INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2015-10-01 | — | — | WO | disclosed |
| EP-2851371-A1 | Glycoclusters and their pharmaceutical use as antibacterials | Centre National de la Recherche Scientifique (CNRS) (FR) | 2015-03-25 | — | — | EP | disclosed |
| US-20140079632-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | UNIVERSITEIT ANTWERPEN (BE) | 2014-03-20 | — | — | US | disclosed |
| WO-2012152807-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | UNIVERSITEIT ANTWERPEN (BE) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017527-B2 | KLK4 inhibitors | KLK4, KLK3, KLK1 | TSHR 3699/4885ALDH1A1 2531/4885TDP1 729/4885 |
| US-20140079632-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | PLAU, SERPINE1, PRSS3 | TSHR 1872/4885ALDH1A1 3114/4885TDP1 1420/4885 |
| US-20170101427-A1 | NOVEL KLK4 INHIBITORS | KLK4, KLK3, KLK1 | TSHR 3647/4885ALDH1A1 2787/4885TDP1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.