Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 6/20 | 0.37 |
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291019 | 0.92 | CYP3A4 (0.46) | CYP3A4DNM1TLR2ODC1LPAR1 | |
| SCHEMBL30340413 | 0.86 | CYP3A4 (0.52) | CYP3A4DNM1TLR2 | |
| SCHEMBL4640889 | 0.85 | DNM1 (0.42) | CYP3A4DNM1TLR2ODC1 | |
| SCHEMBL4117174 | 0.84 | DNM1 (0.52) | CYP3A4DNM1TLR2 | |
| SCHEMBL23270372 | 0.82 | DNM1 (0.37) | CYP3A4DNM1TLR2ODC1 | |
| SCHEMBL23270387 | 0.82 | DNM1 (0.55) | CYP3A4DNM1TLR2 | |
| SCHEMBL6914579 | 0.82 | CYP3A4 (0.56) | CYP3A4DNM1TLR2LPAR1LPAR3 | |
| SCHEMBL23270361 | 0.81 | DNM1 (0.40) | CYP3A4DNM1TLR2 | |
| SCHEMBL23270389 | 0.81 | DNM1 (0.40) | CYP3A4DNM1TLR2 | |
| SCHEMBL19456255 | 0.79 | DNM1 (0.41) | CYP3A4DNM1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373613-B1 | LINEAR AMINE FUNCTIONALIZED POLY(TRIMETHYLENE ETHER) COMPOSITIONS | DU PONT (US) | 2012-11-21 | — | — | EP | disclosed |