Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.40 |
| ▸ | CDK1 | P06493 | 5/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052009 | 0.93 | CCNB2 (0.44) | AHCYCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL13896531 | 0.91 | CCNB2 (0.37) | AHCYCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20052944 | 0.87 | AHCY (0.43) | AHCYCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL13443481 | 0.86 | TDP1 (0.41) | AHCYCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20052010 | 0.84 | CCNB2 (0.40) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL17552180 | 0.83 | AHCY (0.39) | AHCYCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL19221725 | 0.81 | CCNB2 (0.38) | AHCYCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL17445620 | 0.80 | CCNB2 (0.39) | AHCYCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL2718523 | 0.78 | CDK1 (0.59) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL13443484 | 0.78 | L3MBTL1 (0.41) | CCNB2CDK1CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096289-A1 | HYDROXYMETHYL SUBSTITUTED RNA OLIGONUCLEOTIDES AND RNA COMPLEXES | MARINA BIOTECH, INC. (US) | 2013-04-18 | — | — | US | disclosed |
| US-8314227-B2 | Hydroxymethyl substituted RNA oligonucleotides and RNA complexes | MARINA BIOTECH, INC. (US) | 2012-11-20 | — | — | US | disclosed |