Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.66 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.54 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829044 | 0.79 | CYP1A2 (0.65) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 | |
| SCHEMBL3829037 | 0.76 | CYP1A2 (0.60) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 | |
| SCHEMBL580579 | 0.73 | CDK4 (0.66) | CYP1A2ALDH1A1CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL2232185 | 0.72 | CYP1A2 (0.58) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 | |
| SCHEMBL2232188 | 0.72 | ABL1 (0.60) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 | |
| SCHEMBL6506385 | 0.72 | CYP1A2 (0.57) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 | |
| SCHEMBL8809069 | 0.71 | ABL1 (0.68) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 | |
| SCHEMBL14214761 | 0.70 | FGFR3 (0.56) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL1265630 | 0.70 | CYP1A2 (0.60) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 | |
| SCHEMBL15190383 | 0.70 | CYP1A2 (0.51) | CYP1A2ALDH1A1CYP2C19TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069327-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-03-12 | — | — | US | disclosed |
| US-20090069327-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-03-12 | — | — | US | disclosed |
| WO-2007092531-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069327-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | SRC, BMX, FYN | CYP1A2 4285/4885ALDH1A1 4462/4885CYP2C19 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.