SCHEMBL580579

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3608282	0.80	MAPT (0.55)	CDK4GSK3BMKNK1KDM4ENPC1
	Gw683109X SCHEMBL4489938	0.80	CDK4 (1.00)	CDK4GSK3BMKNK1
	SCHEMBL1264404	0.77	EPHX2 (0.54)	CDK4GSK3BMKNK1FGFR1
	SCHEMBL3648590	0.77	MKNK1 (0.61)	CDK4GSK3BMKNK1EIF2AK2RAC1
	SCHEMBL445071	0.75	CDK4 (0.55)	CDK4GSK3BMKNK1EIF2AK2CYP3A4
	SCHEMBL5102956	0.74	CDK4 (0.53)	CDK4GSK3BMKNK1ALDH1A1CYP3A4
	SCHEMBL13897157	0.73	CYP1A2 (0.77)	ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
	SCHEMBL1090555	0.73	CXCR4 (0.61)	CDK4GSK3BMKNK1RAC1KDM4E
	SCHEMBL12015772	0.73	CDK4 (0.53)	CDK4GSK3BMKNK1EIF2AK2FGFR1
	SCHEMBL8233272	0.72	MKNK1 (0.60)	CDK4GSK3BMKNK1EIF2AK2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.